Menopause HRT Protocol Planner

Combine vasomotor symptom intensity, estradiol deficiency, age, and progesterone balance to estimate a starting transdermal estradiol patch dose. Use the suggested mg/day value as a conversation starter with your menopause specialist and adjust based on follow-up labs and risk factors.

Use whole years to align with clinical risk bands (e.g., 45–54, 55+).
Rate hot flashes, night sweats, and sleep disruption on a 1–10 scale (10 = severe, 1 = minimal).
Enter serum estradiol from your latest lab panel (pg/mL).
Leave blank to assume an 8 ng/mL progesterone baseline if you do not have a recent result.

Educational only; hormone therapy must be prescribed and monitored by a healthcare professional.

Examples

  • 52-year-old with severe vasomotor symptoms (score 9), estradiol 25 pg/mL, progesterone 6 ng/mL ⇒ 0.056 mg/day starting dose
  • 48-year-old endurance athlete, symptom score 5, estradiol 35 pg/mL, progesterone 12 ng/mL ⇒ 0.036 mg/day patch recommendation

FAQ

Does this calculator replace medical advice?

No. It provides a data-informed starting point for a conversation with your clinician. Always confirm labs, contraindications, and follow-up frequency with a licensed provider.

How often should I retest hormones?

Most protocols repeat estradiol and progesterone every 8–12 weeks during titration, then every 6–12 months once stable.

What if I use oral or gel formulations?

Convert the suggested mg/day patch dose to the equivalent oral or gel dose using your clinic’s conversion chart. The severity weighting still guides how aggressively to initiate therapy.

Additional Information

  • Dose suggestions cap at 0.100 mg/day to reflect common upper bounds for transdermal estradiol patches.
  • Values below 0.015 mg/day are rounded up to remain practical relative to commercially available patch strengths.
  • Symptom scores above 8 weight dose escalation more aggressively to prioritise relief before gradual tapering.
  • Progesterone inputs modulate the recommendation—lower progesterone bumps estradiol upward to support balance.

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